CATH Domain 4wvfB00

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Ran-specific GTPase-activating protein 1

P62826	RAN_HUMAN Homo sapiens GTP-binding nuclear protein Ran
P41920	YRB1_YEAST Saccharomyces cerevisiae S288C Ran-specific GTPase-activating protein 1

PDB	4WVF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination. Haines, J.D., Herbin, O., de la Hera, B., Vidaurre, O.G., Moy, G.A., Sun, Q., Fung, H.Y., Albrecht, S., Alexandropoulos, K., McCauley, D., Chook, Y.M., Kuhlmann, T., Kidd, G.J., Shacham, S., Casaccia, P. Nat.Neurosci.