CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase

Enzyme Information

5.3.1.16
1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase.
based on mapping to UniProt A1R562
1-(5-phospho-beta-D-ribosyl)-5-((5-phospho-beta-D- ribosylamino)methylideneamino)imidazole-4-carboxamide = 5-((5-phospho-1- deoxy-D-ribulos-1-ylamino)methylideneamino)-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide.
-!- Involved in histidine biosynthesis.

UniProtKB Entries (1)

A1R562
HIS4_PAEAT
Paenarthrobacter aurescens TC1
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase

PDB Structure

PDB 4WD0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of HisAp form Arthrobacter aurescens
MICHALSKA, K., VERDUZCO-CASTRO, E.A., ENDRES, M., BARONA-GOMEZ, F., JOACHIMIAK, A., Midwest Center for Structural Genomics (MCSG)
To Be Published
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