CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.90 | Alpha-Beta Complex | |
3.90.180 | Quinone Oxidoreductase; Chain A, domain 1 | |
3.90.180.10 | Medium-chain alcohol dehydrogenases, catalytic domain |
Domain Context
CATH Clusters
Superfamily | Medium-chain alcohol dehydrogenases, catalytic domain |
Functional Family | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial |
Enzyme Information
1.3.1.104 |
Enoyl-[acyl-carrier-protein] reductase.
based on mapping to UniProt Q8WZM3
An acyl-[acyl-carrier protein] + NADP(+) = a trans-2,3-dehydroacyl-[acyl- carrier protein] + NADPH.
-!- The enzyme completes each cycle of fatty acid elongation by catalyzing the stereospecific reduction of the double bond at position 2 of a growing fatty acid chain, while linked to the acyl- carrier protein, in an NADPH-dependent manner. -!- This entry stands for enzymes whose stereo-specificity with respect to NADP(+) is not known (cf. EC 1.3.1.39, EC 1.3.1.10 and EC 1.3.1.9).
|
UniProtKB Entries (1)
Q8WZM3 |
ETR1_CANTR
Candida tropicalis
Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial
|
PDB Structure
PDB | 4WAS |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The use of ene adducts to study and engineer enoyl-thioester reductases.
Nat.Chem.Biol.
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