CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.710 | Potassium Channel Kv1.1; Chain A |
|
3.30.710.10 | Potassium Channel Kv1.1; Chain A |
Domain Context
CATH Clusters
| Superfamily | Potassium Channel Kv1.1; Chain A |
| Functional Family | Transcription elongation factor |
Enzyme Information
UniProtKB Entries (1)
| P40337 |
VHL_HUMAN
Homo sapiens
Von Hippel-Lindau disease tumor suppressor
|
PDB Structure
| PDB | 4W9C |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities.
J.Med.Chem.
|
