CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family

Enzyme Information

2.1.1.44
L-histidine N(alpha)-methyltransferase.
based on mapping to UniProt A0R5M8
3 S-adenosyl-L-methionine + L-histidine = 3 S-adenosyl-L-homocysteine + hercynine.
-!- Part of the biosynthetic pathway of ergothioneine.

UniProtKB Entries (1)

A0R5M8
EGTD_MYCS2
Mycolicibacterium smegmatis MC2 155
Histidine N-alpha-methyltransferase

PDB Structure

PDB 4UY7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Insights Into the Histidine Trimethylation Activity of Egtd from Mycobacterium Smegmatis.
Jeong, J.H., Cha, H.J., Ha, S.C., Rojviriya, C., Kim, Y.G.
Biochem.Biophys.Res.Commun.