CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1600 | SIR2/SIRT2 'Small Domain' |
|
3.30.1600.10 | SIR2/SIRT2 'Small Domain' |
Domain Context
CATH Clusters
| Superfamily | SIR2/SIRT2 'Small Domain' |
| Functional Family | NAD-dependent protein deacylase sirtuin-5, mitochondrial |
Enzyme Information
| 3.5.1.- |
In linear amides.
based on mapping to UniProt Q6DHI5
|
UniProtKB Entries (2)
| P31327 |
CPSM_HUMAN
Homo sapiens
Carbamoyl-phosphate synthase [ammonia], mitochondrial
|
| Q6DHI5 |
SIR5_DANRE
Danio rerio
NAD-dependent protein deacylase sirtuin-5, mitochondrial
|
PDB Structure
| PDB | 4UTX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Chemical Probing of the Human Sirtuin 5 Active Site Reveals its Substrate Acyl Specificity and Peptide-Based Inhibitors.
Angew.Chem.Int.Ed.Engl.
|