CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family STE20-like serine/threonine-protein kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O94804
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O94804
STK10_HUMAN
Homo sapiens
Serine/threonine-protein kinase 10

PDB Structure

PDB 4USE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Comprehensive Characterization of the Published Kinase Inhibitor Set.
Elkins, J.M., Fedele, V., Szklarz, M., Abdul Azeez, K.R., Salah, E., Mikolajczyk, J., Romanov, S., Sepetov, N., Huang, X.P., Roth, B.L., Al Haj Zen, A., Fourches, D., Muratov, E., Tropsha, A., Morris, J., Teicher, B.A., Kunkel, M., Polley, E., Lackey, K.E., Atkinson, F.L., Overington, J.P., Bamborough, P., Moller, S., Price, D.J., Willson, T.M., Drewry, D.H., Knapp, S., Zuercher, W.J.
Nat.Biotechnol.