CATH Classification

Domain Context

CATH Clusters

Superfamily Calcium-transporting ATPase, cytoplasmic transduction domain A
Functional Family

Enzyme Information

3.6.3.3
Cadmium-exporting ATPase.
based on mapping to UniProt Q3YW59
ATP + H(2)O + Cd(2+)(In) = ADP + phosphate + Cd(2+)(Out).
-!- P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
7.2.2.-
Linked to the hydrolysis of a nucleoside triphosphate.
based on mapping to UniProt Q3YW59
7.2.2.12
P-type Zn(2+) transporter.
based on mapping to UniProt Q3YW59
ATP + H(2)O + Zn(2+)(Side 1) = ADP + phosphate + Zn(2+)(Side 2).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- The enzyme, present in prokaryotes and photosynthetic eukaryotes, exports Zn(2+) and the related cations Cd(2+) and Pb(2+). -!- Formerly EC 3.6.3.5.

UniProtKB Entries (1)

Q3YW59
ZNTA_SHISS
Shigella sonnei Ss046
Zinc/cadmium/lead-transporting P-type ATPase

PDB Structure

PDB 4UMV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and Mechanism of Zn(2+)-Transporting P-Type Atpases.
Wang, K., Sitsel, O., Meloni, G., Autzen, H.E., Andersson, M., Klymchuk, T., Nielsen, A.M., Rees, D.C., Nissen, P., Gourdon, P.
Nature
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