CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.90 | Alpha-Beta Complex | |
3.90.340 | Nitric Oxide Synthase; Chain A, domain 1 | |
3.90.340.10 | Nitric Oxide Synthase; Chain A, domain 1 |
Domain Context
CATH Clusters
Superfamily | Nitric Oxide Synthase; Chain A, domain 1 |
Functional Family | Nitric oxide synthase oxygenase |
Enzyme Information
1.14.14.47 |
Nitric-oxide synthase (flavodoxin).
based on mapping to UniProt O34453
2 L-arginine + 3 reduced flavodoxin + 4 O(2) = 2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H(2)O.
-!- The enzyme, found in bacteria and archaea, consist of only an oxygenase domain and functions together with bacterial ferredoxins or flavodoxins. -!- The orthologous enzymes from plants and animals also contain a reductase domain and use only NADPH as the electron donor (cf. EC 1.14.13.39). -!- Formerly EC 1.14.13.165.
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UniProtKB Entries (1)
O34453 |
NOSO_BACSU
Bacillus subtilis subsp. subtilis str. 168
Nitric oxide synthase oxygenase
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PDB Structure
PDB | 4UGU |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase.
Biochemistry
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