CATH Classification

Domain Context

CATH Clusters

Superfamily 2.10.110.20
Functional Family lysine-specific demethylase 6A isoform X2

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt O14607

UniProtKB Entries (1)

O14607
UTY_HUMAN
Homo sapiens
Histone demethylase UTY

PDB Structure

PDB 4UF0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.
Johansson, C., Velupillai, S., Tumber, A., Szykowska, A., Hookway, E.S., Nowak, R.P., Strain-Damerell, C., Gileadi, C., Philpott, M., Burgess-Brown, N., Wu, N., Kopec, J., Nuzzi, A., Steuber, H., Egner, U., Badock, V., Munro, S., Lathangue, N.B., Westaway, S., Brown, J., Athanasou, N., Prinjha, R., Brennan, P.E., Oppermann, U.
Nat.Chem.Biol.
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