CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.410 | Cholesterol Oxidase; domain 2 |
|
3.30.410.40 |
Domain Context
CATH Clusters
| Superfamily | 3.30.410.40 |
| Functional Family | 5-(hydroxymethyl)furfural oxidase |
Enzyme Information
| 1.1.3.47 |
5-(hydroxymethyl)furfural oxidase.
based on mapping to UniProt E4QP00
5-(hydroxymethyl)furfural + 3 O(2) + 2 H(2)O = furan-2,5-dicarboxylate + 3 H(2)O(2).
-!- The enzyme, characterized from the bacterium Methylovorus sp. strain MP688, is involved in the degradation and detoxification of 5-(hydroxymethyl)furfural. -!- The enzyme acts only on alcohol groups and requires the spontaneous hydration of aldehyde groups for their oxidation. -!- The enzyme has a broad substrate range that overlaps with EC 1.1.3.7.
|
| 1.8.3.- |
With oxygen as acceptor.
based on mapping to UniProt E4QP00
|
UniProtKB Entries (1)
| E4QP00 |
HMFO_METS6
Methylovorus sp. MP688
5-(hydroxymethyl)furfural oxidase
|
PDB Structure
| PDB | 4UDP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase
Acs Catalysis
|
