CATH Domain 4ucwQ00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.645	Cytochrome-c3 Hydrogenase; chain B
	1.10.645.10	Cytochrome-c3 Hydrogenase, chain B

Domain Context

CATH Clusters

Superfamily	Cytochrome-c3 Hydrogenase, chain B
Functional Family	Hydrogenase 2 large subunit

Enzyme Information

1.12.2.1

Cytochrome-c3 hydrogenase.

based on mapping to UniProt P18188

H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.

-!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). -!- Methylene blue and other acceptors can also be reduced.

UniProtKB Entries (1)

P18187

PHNS_DESFR

Desulfovibrio fructosivorans

Periplasmic [NiFe] hydrogenase small subunit

PDB Structure

PDB	4UCW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A Threonine Stabilizes the Nic and Nir Catalytic Intermediates of [Nife]-Hydrogenase. Abou-Hamdan, A., Ceccaldi, P., Lebrette, H., Gutierrez-Sanz, O., Richaud, P., Cournac, L., Guigliarelli, B., De Lacey, A.L., Leger, C., Volbeda, A., Burlat, B., Dementin, S. J.Biol.Chem.