CATH Domain 4txsA03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.270	Reverse transcriptase/Diguanylate cyclase domain

Domain Context

CATH Clusters

Superfamily	3.30.70.270
Functional Family	Genome polyprotein

Enzyme Information

UniProtKB Entries (1)

D0PY27_9HEPC

Hepacivirus C

RNA-directed RNA polymerase

PDB Structure

PDB	4TXS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Chen, X., Qin, S., Chen, S., Li, J., Li, L., Wang, Z., Wang, Q., Lin, J., Yang, C., Shui, W. Sci Rep