CATH Domain 4tt2A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	ATPase family AAA domain-containing protein 2

Enzyme Information

3.6.1.3

Adenosinetriphosphatase.

based on mapping to UniProt Q6PL18

ATP + H(2)O = ADP + phosphate.

-!- Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39. -!- The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA. -!- Formerly EC 3.6.1.4.

UniProtKB Entries (1)

Q6PL18

ATAD2_HUMAN

Homo sapiens

ATPase family AAA domain-containing protein 2

PDB Structure

PDB	4TT2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2. Poncet-Montange, G., Zhan, Y., Bardenhagen, J.P., Petrocchi, A., Leo, E., Shi, X., Lee, G.R., Leonard, P.G., Geck Do, M.K., Cardozo, M.G., Andersen, J.N., Palmer, W.S., Jones, P., Ladbury, J.E. Biochem.J.