CATH Domain 4s0uA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.100	Mannose-Binding Protein A; Chain A
	3.10.100.10	Mannose-Binding Protein A, subunit A

Domain Context

CATH Clusters

Superfamily	Mannose-Binding Protein A, subunit A
Functional Family	NKG2-D type II integral membrane protein

Enzyme Information

UniProtKB Entries (1)

NKG2D_HUMAN

Homo sapiens

NKG2-D type II integral membrane protein

PDB Structure

PDB	4S0U
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding. Zuo, J., Willcox, C.R., Mohammed, F., Davey, M., Hunter, S., Khan, K., Antoun, A., Katakia, P., Croudace, J., Inman, C., Parry, H., Briggs, D., Malladi, R., Willcox, B.E., Moss, P. Sci Signal