CATH Classification

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

Q9J006
Q9J006_9HIV1
Human immunodeficiency virus 1
Protease

PDB Structure

PDB 4RVJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Enhanced antiviral activity by the P2-tris-tetrahydrofuran moiety of GRL-0519, a novel nonpeptidic HIV-1 protease inhibitor (PI), against multi-PI-resistant and highly darunavir-resistant strains of HIV-1
Yedidi, R.S., Maeda, K., Aoki, M., Garimella, H., Rao, K.V., Akasapu, S., Davis, D.A., Kaufman, J.D., Das, D., Wingfield, P.T., Amano, M., Ghosh, A.K., Mitsuya, H.
To be Published