CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.40.20
Functional Family Transitional endoplasmic reticulum ATPase

Enzyme Information

3.6.4.6
Vesicle-fusing ATPase.
based on mapping to UniProt Q7KN62
ATP + H(2)O = ADP + phosphate.
-!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. -!- They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. -!- They include peroxin, which apparently is involved in Zellweger's syndrome.

UniProtKB Entries (1)

Q7KN62
TERA_DROME
Drosophila melanogaster
Transitional endoplasmic reticulum ATPase TER94

PDB Structure

PDB 4RV0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of TN complex
Hao, Q., Jiao, S., Shi, Z.B., Zhou, Z.C.
To be Published
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