CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Calcium-dependent protein kinase 4

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q8IBS5
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q8IBS5
CDPK4_PLAF7
Plasmodium falciparum 3D7
Calcium-dependent protein kinase 4

PDB Structure

PDB 4RGJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Apo crystal structure of CDPK4 from Plasmodium falciparum, PF3D7_0717500
Wernimont, A.K., Walker, J.R., Hutchinson, A., Seitova, A., He, H., Loppnau, P., Neculai, M., Amani, M., Lin, Y.H., Ravichandran, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Lovato, D.V.
To be Published