CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.8 | Helicase, Ruva Protein; domain 3 |
|
1.10.8.1190 | Papain-like viral protease, thumb domain |
Domain Context
CATH Clusters
| Superfamily | 1.10.8.1190 |
| Functional Family | ORF1ab polyprotein |
Enzyme Information
UniProtKB Entries (2)
| M4STU1 |
M4STU1_9BETC
Human betacoronavirus 2c Jordan-N3/2012
ORF1ab protein
|
| P62987 |
RL40_HUMAN
Homo sapiens
Ubiquitin-60S ribosomal protein L40
|
PDB Structure
| PDB | 4RF1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression.
J.Biol.Chem.
|
