CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.8 | Helicase, Ruva Protein; domain 3 | |
1.10.8.1190 | Papain-like viral protease, thumb domain |
Domain Context
CATH Clusters
Superfamily | 1.10.8.1190 |
Functional Family | ORF1ab polyprotein |
Enzyme Information
UniProtKB Entries (2)
M4STU1 |
M4STU1_9BETC
Human betacoronavirus 2c Jordan-N3/2012
ORF1ab protein
|
P62987 |
RL40_HUMAN
Homo sapiens
Ubiquitin-60S ribosomal protein L40
|
PDB Structure
PDB | 4RF0 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression.
J.Biol.Chem.
|