CATH Domain 4r8uB03

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.150	DNA polymerase; domain 1
	1.10.150.20	5' to 3' exonuclease, C-terminal subdomain

Domain Context

CATH Clusters

Superfamily	5' to 3' exonuclease, C-terminal subdomain
Functional Family	DNA polymerase IV

Enzyme Information

2.7.7.7

DNA-directed DNA polymerase.

based on mapping to UniProt Q47155

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q47155

DPO4_ECOLI

Escherichia coli K-12

DNA polymerase IV

PDB Structure

PDB	4R8U
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Fast native-SAD phasing for routine macromolecular structure determination Weinert, T., Olieric, V., Waltersperger, S., Panepucci, E., Chen, L., Zhang, H., Zhou, D., Rose, J., Ebihara, A., Kuramitsu, S., Li, D., Howe, N., Schnapp, G., Pautsch, A., Bargsten, K., Prota, A.E., Surana, P., Kottur, J., Nair, D.T., Basilico, F., Cecatiello, V., Pasqualato, S., Boland, A., Weichenrieder, O., Wang, B.C., Steinmetz, M.O., Caffrey, M., Wang, M. Nat.Methods