CATH Classification

Domain Context

CATH Clusters

Superfamily Peptidase M1, alanyl aminopeptidase, C-terminal domain
Functional Family M1 family aminopeptidase

Enzyme Information

3.4.11.-
Aminopeptidases.
based on mapping to UniProt O96935

UniProtKB Entries (1)

O96935
AMP1_PLAFQ
Plasmodium falciparum FcB1/Columbia
M1 family aminopeptidase

PDB Structure

PDB 4R5V
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors.
Mistry, S.N., Drinkwater, N., Ruggeri, C., Sivaraman, K.K., Loganathan, S., Fletcher, S., Drag, M., Paiardini, A., Avery, V.M., Scammells, P.J., McGowan, S.
J.Med.Chem.
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