CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.880 | Class I glutamine amidotransferase (GATase) domain |
Domain Context
CATH Clusters
Superfamily | 3.40.50.880 |
Functional Family |
Enzyme Information
4.2.1.130 |
D-lactate dehydratase.
based on mapping to UniProt Q10356
(R)-lactate = methylglyoxal + H(2)O.
-!- The enzyme, described from the fungi Candida albicans and Schizosaccharomyces pombe, converts 2-oxopropanal to (R)-lactate in a single glutathione (GSH)-independent step. -!- The other known route for this conversion is the two-step GSH- dependent pathway catalyzed by EC 4.4.1.5 and EC 3.1.2.6.
|
UniProtKB Entries (1)
Q10356 |
DJ1_SCHPO
Schizosaccharomyces pombe 972h-
Glutathione-independent glyoxalase DJ-1
|
PDB Structure
PDB | 4QYT |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Influence of peptide dipoles and hydrogen bonds on reactive cysteine pK(a) values in fission yeast DJ-1.
Febs J.
|