CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.309 | Aldehyde Dehydrogenase; Chain A, domain 2 |
|
3.40.309.10 | Aldehyde Dehydrogenase; Chain A, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Aldehyde Dehydrogenase; Chain A, domain 2 |
| Functional Family | Aldehyde dehydrogenase |
Enzyme Information
| 1.2.1.3 |
Aldehyde dehydrogenase (NAD(+)).
based on mapping to UniProt P51648
An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
-!- Wide specificity, including oxidation of D-glucuronolactone to D-glucarate. -!- Formerly EC 1.1.1.70.
|
UniProtKB Entries (1)
| P51648 |
AL3A2_HUMAN
Homo sapiens
Fatty aldehyde dehydrogenase
|
PDB Structure
| PDB | 4QGK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A gatekeeper helix determines the substrate specificity of Sjogren-Larsson Syndrome enzyme fatty aldehyde dehydrogenase.
Nat Commun
|
