CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Basic phospholipase A2 homolog

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt D0VX11
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

D0VX11
D0VX11_DABRR
Daboia russelii pulchella
Phospholipase A2 VRV-PL-VIIIa

PDB Structure

PDB 4QGD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures and binding studies of the complexes of phospholipase A2 with five inhibitors
Shukla, P.K., Gautam, L., Sinha, M., Kaur, P., Sharma, S., Singh, T.P.
Biochim.Biophys.Acta