CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.462 | Vanillyl-alcohol Oxidase; Chain A, domain 3 |
|
3.40.462.20 |
Domain Context
CATH Clusters
| Superfamily | 3.40.462.20 |
| Functional Family |
Enzyme Information
| 1.21.3.3 |
Reticuline oxidase.
based on mapping to UniProt P30986
(S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2).
-!- Acts on (S)-reticuline and related compounds, converting the N-methyl group into the methylene bridge ('berberine bridge') of (S)- tetrahydroprotoberberines. -!- The product of the reaction, (S)-scoulerine, is a precursor of protopine, protoberberine and benzophenanthridine alkaloid biosynthesis in plants. -!- Formerly EC 1.5.3.9.
|
UniProtKB Entries (1)
| P30986 |
RETO_ESCCA
Eschscholzia californica
Reticuline oxidase
|
PDB Structure
| PDB | 4PZF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction.
Febs J.
|
