CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleic acid-binding proteins
Functional Family

Enzyme Information

2.7.7.50
mRNA guanylyltransferase.
based on mapping to UniProt P40997
GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA.
-!- Can modify also synthetic poly(A) and poly(G) to form the structures m(7)G(5')pppAn and m(7)G(5')pppGn.

UniProtKB Entries (1)

P36594
RPB1_SCHPO
Schizosaccharomyces pombe 972h-
DNA-directed RNA polymerase II subunit rpb1

PDB Structure

PDB 4PZ6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.
Doamekpor, S.K., Sanchez, A.M., Schwer, B., Shuman, S., Lima, C.D.
Genes Dev.