CATH Domain 4pvvA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1190	UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase
	3.40.1190.20	Ribokinase

Domain Context

CATH Clusters

Superfamily	3.40.1190.20
Functional Family	Adenosine kinase

Enzyme Information

2.7.1.20

Adenosine kinase.

based on mapping to UniProt P9WID5

ATP + adenosine = ADP + AMP.

-!- 2-aminoadenosine can also act as acceptor.

UniProtKB Entries (1)

ADOK_MYCTU

Mycobacterium tuberculosis H37Rv

Adenosine kinase

PDB Structure

PDB	4PVV
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides Snasel, J., Naus, P., Dostal, J., Hnizda, A., Fanfrlik, J., Brynda, J., Bourderioux, A., Dusek, M., Dvorakova, H., Stolarikova, J., Zabranska, H., Pohl, R., Konecny, P., Dzubak, P., Votruba, I., Hajduch, M., Rezacova, P., Veverka, V., Hocek, M., Pichova, I. J.Med.Chem.