CATH Domain 4pv5B00

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.180	2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1
	3.10.180.10	2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1

Superfamily	2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
Functional Family	Lactoylglutathione lyase

4.4.1.5

Lactoylglutathione lyase.

based on mapping to UniProt Q9CPU0

(R)-S-lactoylglutathione = glutathione + methylglyoxal.

-!- Also acts on 3-phosphoglycerol-glutathione.

LGUL_MOUSE

Mus musculus

Lactoylglutathione lyase

PDB	4PV5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for 18-beta-glycyrrhetinic acid as a novel non-GSH analog glyoxalase I inhibitor Zhang, H., Huang, Q., Zhai, J., Zhao, Y.N., Zhang, L.P., Chen, Y.Y., Zhang, R.W., Li, Q., Hu, X.P. Acta Pharmacol.Sin.