CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.10 | Deoxyribonuclease I; Chain A |
|
3.60.10.10 | Endonuclease/exonuclease/phosphatase |
Domain Context
CATH Clusters
| Superfamily | Endonuclease/exonuclease/phosphatase |
| Functional Family | Tyrosyl-DNA phosphodiesterase 2 |
Enzyme Information
| 3.1.4.- |
Phosphoric diester hydrolases.
based on mapping to UniProt Q9JJX7
|
UniProtKB Entries (1)
| Q9JJX7 |
TYDP2_MOUSE
Mus musculus
Tyrosyl-DNA phosphodiesterase 2
|
PDB Structure
| PDB | 4PUQ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2DNA and Top2RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2).
J.Biol.Chem.
|
