CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.167 | Regulator of G-protein Signalling 4; domain 2 | |
1.10.167.10 | Regulator of G-protein Signalling 4, domain 2 |
Domain Context
CATH Clusters
Superfamily | Regulator of G-protein Signalling 4, domain 2 |
Functional Family |
Enzyme Information
2.7.11.14 |
Rhodopsin kinase.
based on mapping to UniProt P28327
ATP + [rhodopsin] = ADP + [rhodopsin] phosphate.
-!- Acts on the bleached or activated form of rhodopsin. -!- Also phosphorylates the beta-adrenergic receptor, but more slowly. -!- Does not act on casein, histones or phosphovitin. -!- Inhibited by Zn(2+) and digitonin (cf. EC 2.7.11.15 and EC 2.7.11.16). -!- Formerly EC 2.7.1.97 and EC 2.7.1.125.
|
UniProtKB Entries (1)
P28327 |
RK_BOVIN
Bos taurus
Rhodopsin kinase
|
PDB Structure
PDB | 4PNI |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Identification and structure-function analysis of subfamily selective g protein-coupled receptor kinase inhibitors.
Acs Chem.Biol.
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