CATH Classification

Domain Context

CATH Clusters

Superfamily Regulator of G-protein Signalling 4, domain 2
Functional Family

Enzyme Information

2.7.11.14
Rhodopsin kinase.
based on mapping to UniProt P28327
ATP + [rhodopsin] = ADP + [rhodopsin] phosphate.
-!- Acts on the bleached or activated form of rhodopsin. -!- Also phosphorylates the beta-adrenergic receptor, but more slowly. -!- Does not act on casein, histones or phosphovitin. -!- Inhibited by Zn(2+) and digitonin (cf. EC 2.7.11.15 and EC 2.7.11.16). -!- Formerly EC 2.7.1.97 and EC 2.7.1.125.

UniProtKB Entries (1)

P28327
RK_BOVIN
Bos taurus
Rhodopsin kinase

PDB Structure

PDB 4PNI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification and structure-function analysis of subfamily selective g protein-coupled receptor kinase inhibitors.
Homan, K.T., Larimore, K.M., Elkins, J.M., Szklarz, M., Knapp, S., Tesmer, J.J.
Acs Chem.Biol.
CATH-Gene3D is a Global Biodata Core Resource Learn more...