CATH Classification
Domain Context
CATH Clusters
| Superfamily | Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal |
| Functional Family | L-lactate dehydrogenase |
Enzyme Information
| 1.1.1.27 |
L-lactate dehydrogenase.
based on mapping to UniProt Q27743
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.
|
UniProtKB Entries (1)
| Q27743 |
LDH_PLAFD
Plasmodium falciparum CDC/Honduras
L-lactate dehydrogenase
|
PDB Structure
| PDB | 4PLZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.
Elife
|
