CATH Domain 4pf3A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.565	Retinoid X Receptor
	1.10.565.10	Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily	Retinoid X Receptor
Functional Family	Androgen receptor variant

Enzyme Information

UniProtKB Entries (1)

MCR_HUMAN

Homo sapiens

Mineralocorticoid receptor

PDB Structure

PDB	4PF3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of 6-[5-(4-fluorophenyl)-3-methyl-pyrazol-4-yl]-benzoxazin-3-one derivatives as novel selective nonsteroidal mineralocorticoid receptor antagonists Hasui, T., Ohyabu, N., Ohra, T., Fuji, K., Sugimoto, T., Fujimoto, J., Asano, K., Oosawa, M., Shiotani, S., Nishigaki, N., Kusumoto, K., Matsui, H., Mizukami, A., Habuka, N., Sogabe, S., Endo, S., Ono, M., Siedem, C.S., Tang, T.P., Gauthier, C., De Meese, L.A., Boyd, S.A., Fukumoto, S. Bioorg.Med.Chem.