CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.510 | Transferase(Phosphotransferase); domain 1 |
|
1.10.510.10 | Transferase(Phosphotransferase) domain 1 |
Domain Context
CATH Clusters
| Superfamily | Transferase(Phosphotransferase) domain 1 |
| Functional Family | Serine/threonine-protein kinase RAD53 |
Enzyme Information
| 2.7.12.1 |
Dual-specificity kinase.
based on mapping to UniProt P22216
ATP + a protein = ADP + a phosphoprotein.
-!- This family of enzymes can phosphorylate both Ser/Thr and Tyr residues. -!- Formerly EC 2.7.1.37.
|
UniProtKB Entries (1)
| P22216 |
RAD53_YEAST
Saccharomyces cerevisiae S288C
Serine/threonine-protein kinase RAD53
|
PDB Structure
| PDB | 4PDS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of Rad53 kinase activation by dimerization and activation segment exchange.
Cell Signal.
|
