CATH Domain 4p74C01

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.930	BirA Bifunctional Protein; domain 2
	3.30.930.10	Bira Bifunctional Protein; Domain 2

Superfamily	Bira Bifunctional Protein; Domain 2
Functional Family	Phenylalanine--tRNA ligase alpha subunit

6.1.1.20

Phenylalanine--tRNA ligase.

based on mapping to UniProt Q9I0A3

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).

SYFA_PSEAE

Pseudomonas aeruginosa PAO1

Phenylalanine--tRNA ligase alpha subunit

PDB	4P74
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability. Abibi, A., Ferguson, A.D., Fleming, P.R., Gao, N., Hajec, L.I., Hu, J., Laganas, V.A., McKinney, D.C., McLeod, S.M., Prince, D.B., Shapiro, A.B., Buurman, E.T. J.Biol.Chem.