CATH Classification

Domain Context

CATH Clusters

Superfamily Phenylalanyl-trna Synthetase, Chain B, domain 3
Functional Family Phenylalanine--tRNA ligase beta subunit

Enzyme Information

6.1.1.20
Phenylalanine--tRNA ligase.
based on mapping to UniProt Q9I0A4
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).

UniProtKB Entries (1)

Q9I0A3
SYFA_PSEAE
Pseudomonas aeruginosa PAO1
Phenylalanine--tRNA ligase alpha subunit

PDB Structure

PDB 4P74
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability.
Abibi, A., Ferguson, A.D., Fleming, P.R., Gao, N., Hajec, L.I., Hu, J., Laganas, V.A., McKinney, D.C., McLeod, S.M., Prince, D.B., Shapiro, A.B., Buurman, E.T.
J.Biol.Chem.
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