CATH Classification

Domain Context

CATH Clusters

Superfamily Bira Bifunctional Protein; Domain 2
Functional Family Threonine--tRNA ligase

Enzyme Information

6.1.1.3
Threonine--tRNA ligase.
based on mapping to UniProt P0A8M3
ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).

UniProtKB Entries (1)

P0A8M3
SYT_ECOLI
Escherichia coli K-12
Threonine--tRNA ligase

PDB Structure

PDB 4P3O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Fang, P., Yu, X., Jeong, S.J., Mirando, A., Chen, K., Chen, X., Kim, S., Francklyn, C.S., Guo, M.
Nat Commun
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