CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.630 | Aminopeptidase | |
3.40.630.10 | Zn peptidases |
Domain Context
CATH Clusters
Superfamily | Zn peptidases |
Functional Family | Carboxypeptidase B2 |
Enzyme Information
3.4.17.20 |
Carboxypeptidase U.
based on mapping to UniProt Q96IY4
Release of C-terminal Arg and Lys from a polypeptide.
-!- Pro-carboxypeptidase U in plasma is activated by thrombin or plasmin during clotting to form the unstable carboxypeptidase U. -!- Activity similar to that of the more stable lysine carboxypeptidase, except no preference is shown for Lys over Arg. -!- Belongs to peptidase family M14.
|
UniProtKB Entries (1)
Q96IY4 |
CBPB2_HUMAN
Homo sapiens
Carboxypeptidase B2
|
PDB Structure
PDB | 4P10 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Design and synthesis of conformationally restricted inhibitors of active thrombin activatable fibrinolysis inhibitor (TAFIa).
Bioorg.Med.Chem.
|