CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.3020 | alpha-amino acid ester hydrolase ( Helical cap domain) |
|
1.10.3020.10 | alpha-amino acid ester hydrolase ( Helical cap domain) |
Domain Context
CATH Clusters
| Superfamily | alpha-amino acid ester hydrolase ( Helical cap domain) |
| Functional Family |
Enzyme Information
| 3.1.1.84 |
Cocaine esterase.
based on mapping to UniProt Q9L9D7
Cocaine + H(2)O = ecgonine methyl ester + benzoate.
-!- Rhodococcus sp. strain MB1 and Pseudomonas maltophilia strain MB11L can utilize cocaine as sole source of carbon and energy.
|
UniProtKB Entries (1)
| Q9L9D7 |
COCE_RHOSM
Rhodococcus sp. MB1 'Bresler 1999'
Cocaine esterase
|
PDB Structure
| PDB | 4P08 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification.
Acs Chem.Biol.
|
