CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.437 | Apoptosis Regulator Bcl-x | |
1.10.437.10 | Blc2-like |
Domain Context
CATH Clusters
Superfamily | Blc2-like |
Functional Family | Induced myeloid leukemia cell differentiation protein Mcl-1 |
Enzyme Information
UniProtKB Entries (1)
Q07820 |
MCL1_HUMAN
Homo sapiens
Induced myeloid leukemia cell differentiation protein Mcl-1
|
PDB Structure
PDB | 4OQ5 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein.
Bioorg.Med.Chem.Lett.
|