CATH Domain 4op2A01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10490	Glucose-6-phosphate isomerase like protein; domain 1

Domain Context

CATH Clusters

Superfamily	Glucose-6-phosphate isomerase like protein; domain 1
Functional Family	Glucokinase regulatory protein

Enzyme Information

UniProtKB Entries (1)

GCKR_HUMAN

Homo sapiens

Glucokinase regulatory protein

PDB Structure

PDB	4OP2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis. Tamayo, N.A., Norman, M.H., Bartberger, M.D., Hong, F.T., Bo, Y., Liu, L., Nishimura, N., Yang, K.C., Tadesse, S., Fotsch, C., Chen, J., Chmait, S., Cupples, R., Hale, C., Jordan, S.R., Lloyd, D.J., Sivits, G., Van, G., St Jean, D.J. J.Med.Chem.