CATH Classification

Domain Context

CATH Clusters

Superfamily Farnesyl Diphosphate Synthase
Functional Family Selina-4(15),7(11)-diene synthase ((2E,6E)-farnesyl diphosphate cyclizing)

Enzyme Information

4.2.3.181
Selina-4(15),7(11)-diene synthase.
based on mapping to UniProt B5HDJ6
(2E,6E)-farnesyl diphosphate = selina-4(15),7(11)-diene + diphosphate.
-!- Isolated from the bacteria Streptomyces pristinaespiralis and S.somaliensis.

UniProtKB Entries (1)

B5HDJ6
SEDS_STRE2
Streptomyces pristinaespiralis ATCC 25486
Selina-4(15),7(11)-diene synthase ((2E,6E)-farnesyl diphosphate cyclizing)

PDB Structure

PDB 4OKZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Induced-fit mechanism in class i terpene cyclases.
Baer, P., Rabe, P., Fischer, K., Citron, C.A., Klapschinski, T.A., Groll, M., Dickschat, J.S.
Angew.Chem.Int.Ed.Engl.
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