CATH Domain 4oksA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Genome polyprotein

Enzyme Information

UniProtKB Entries (1)

K4KA16_9HEPC

Hepacivirus C

Genome polyprotein

PDB Structure

PDB	4OKS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus. Laplante, S.R., Padyana, A.K., Abeywardane, A., Bonneau, P., Cartier, M., Coulombe, R., Jakalian, A., Wildeson-Jones, J., Li, X., Liang, S., McKercher, G., White, P., Zhang, Q., Taylor, S.J. J.Med.Chem.