CATH Classification

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Bile acid receptor isoform 4

Enzyme Information

UniProtKB Entries (1)

Q96RI1
NR1H4_HUMAN
Homo sapiens
Bile acid receptor

PDB Structure

PDB 4OIV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor alpha (FXR alpha ) in Stabilizing the Homodimerization of the Receptor.
Xu, X., Xu, X., Liu, P., Zhu, Z.Y., Chen, J., Fu, H.A., Chen, L.L., Hu, L.H., Shen, X.
J.Biol.Chem.
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