CATH Classification

Domain Context

CATH Clusters

Superfamily Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q5SHR6
RPOA_THET8
Thermus thermophilus HB8
DNA-directed RNA polymerase subunit alpha

PDB Structure

PDB 4OIP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Zhang, Y., Degen, D., Ho, M.X., Sineva, E., Ebright, K.Y., Ebright, Y.W., Mekler, V., Vahedian-Movahed, H., Feng, Y., Yin, R., Tuske, S., Irschik, H., Jansen, R., Maffioli, S., Donadio, S., Arnold, E., Ebright, R.H.
Elife