CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.470 | D-amino Acid Aminotransferase; Chain A, domain 1 |
|
3.30.470.20 | ATP-grasp fold, B domain |
Domain Context
CATH Clusters
| Superfamily | ATP-grasp fold, B domain |
| Functional Family | Phosphoribosylaminoimidazole-succinocarboxamide synthase |
Enzyme Information
| 6.3.2.6 |
Phosphoribosylaminoimidazolesuccinocarboxamide synthase.
based on mapping to UniProt O57978
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamido)succinate.
-!- Forms part of the purine biosynthesis pathway.
|
UniProtKB Entries (1)
| O57978 |
PUR7_PYRHO
Pyrococcus horikoshii OT3
Phosphoribosylaminoimidazole-succinocarboxamide synthase
|
PDB Structure
| PDB | 4O7S |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
SAICAR synthetase (Type-2) in complex with TMP/TDP
To be Published
|