CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase ATXR5

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt B9RU15
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

B9RU15
ATXR5_RICCO
Ricinus communis
Probable Histone-lysine N-methyltransferase ATXR5

PDB Structure

PDB 4O30
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication.
Jacob, Y., Bergamin, E., Donoghue, M.T., Mongeon, V., LeBlanc, C., Voigt, P., Underwood, C.J., Brunzelle, J.S., Michaels, S.D., Reinberg, D., Couture, J.F., Martienssen, R.A.
Science
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