CATH Domain 4o1vA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.210	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A
	2.60.210.10	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A

Domain Context

CATH Clusters

Superfamily	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A
Functional Family	Speckle-type POZ protein-like

Enzyme Information

UniProtKB Entries (1)

PTEN_HUMAN

Homo sapiens

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

PDB Structure

PDB	4O1V
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub in Kidney Cancer. Li, G., Ci, W., Karmakar, S., Chen, K., Dhar, R., Fan, Z., Guo, Z., Zhang, J., Ke, Y., Wang, L., Zhuang, M., Hu, S., Li, X., Zhou, L., Li, X., Calabrese, M.F., Watson, E.R., Prasad, S.M., Rinker-Schaeffer, C., Eggener, S.E., Stricker, T., Tian, Y., Schulman, B.A., Liu, J., White, K.P. Cancer Cell