CATH Domain 4o1pA03

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1440	de novo design (two linked rop proteins)
	1.20.1440.180	KEN domain

Domain Context

CATH Clusters

Superfamily	KEN domain
Functional Family	Ribonuclease L

Enzyme Information

UniProtKB Entries (1)

A5H025_PIG

Sus scrofa

Ribonuclease L

PDB Structure

PDB	4O1P
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity. Huang, H., Zeqiraj, E., Dong, B., Jha, B.K., Duffy, N.M., Orlicky, S., Thevakumaran, N., Talukdar, M., Pillon, M.C., Ceccarelli, D.F., Wan, L.C., Juang, Y.C., Mao, D.Y., Gaughan, C., Brinton, M.A., Perelygin, A.A., Kourinov, I., Guarne, A., Silverman, R.H., Sicheri, F. Mol.Cell