CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.499 | Aconitase; domain 3 |
|
3.30.499.10 | Aconitase, domain 3 |
Domain Context
CATH Clusters
| Superfamily | Aconitase, domain 3 |
| Functional Family |
Enzyme Information
| 4.2.1.35 |
(R)-2-methylmalate dehydratase.
based on mapping to UniProt P81291
(R)-2-methylmalate = 2-methylmaleate + H(2)O.
|
| 4.2.1.31 |
Maleate hydratase.
based on mapping to UniProt P81291
(R)-malate = maleate + H(2)O.
|
| 4.2.1.33 |
3-isopropylmalate dehydratase.
based on mapping to UniProt P81291
(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
-!- Forms part of the leucine-biosynthesis pathway. -!- Brings about the interconversion of the two isomers of isopropylmalate.
|
UniProtKB Entries (1)
| P81291 |
LEUC_METJA
Methanocaldococcus jannaschii DSM 2661
Isopropylmalate/citramalate isomerase large subunit
|
PDB Structure
| PDB | 4NQY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural characterization and comparison of the large subunits of IPM isomerase and homoaconitase from Methanococcus jannaschii
Acta Crystallogr.,Sect.D
|